Kratom—a plant native to Southeast Asia—has gained attention in recent years, especially among
individuals affected by opioid use. Marketed as a natural remedy for pain, anxiety, and even opioid
withdrawal, kratom is often seen as a safer alternative to prescription opioids. But is it truly safe or
effective? Let’s explore what kratom is, how it works, and what current research and public health
experts say about its use—especially for those in or considering recovery from opioid use disorder
(OUD).
What Is Kratom?
Kratom (Mitragyna speciosa) is a tropical tree whose leaves contain compounds—primarily
mitragynine and 7-hydroxymitragynine (7-OH)—that interact with opioid receptors in the brain.
At low doses, kratom acts as a stimulant; at higher doses, it can produce sedative and opioid-like
effects[1].
Kratom is sold in various forms: powders, capsules, teas, extracts, and even gummies. It’s widely
available online and in convenience stores, often marketed as a dietary supplement or herbal
remedy.
Why Do People Use Kratom?
Many people turn to kratom for:

  • Pain relief
  • Mood enhancement
  • Energy and focus
  • Managing opioid withdrawal symptoms
  • Reducing cravings for opioids
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    Some individuals in recovery report that kratom helped them transition away from prescription
    opioids or illicit drugs. In a study from Johns Hopkins University, 87% of kratom users said it helped
    relieve withdrawal symptoms, and 80% reported reduced cravings[2].
    The Risks of Kratom Use
    Despite anecdotal reports of benefits, kratom is not without risks:
  • Addiction and dependence: Kratom can be habit-forming, especially with long-term use.
    Withdrawal symptoms may resemble those of opioids[3].
  • Adverse health effects: These include liver toxicity, seizures, psychosis, and cardiovascular
    issues[4].
  • Contamination: Some kratom products have been found to contain heavy metals, bacteria
    (like salmonella), or synthetic additives[5].
  • Lack of regulation: The FDA has not approved kratom for any medical use. It is not legally
    marketed as a drug, dietary supplement, or food additive in the U.S.[4].
    Kratom and Opioid Recovery: A Complex Relationship
    For individuals in recovery from OUD, kratom presents a dilemma. While some view it as a harmreduction tool, others see it as a potential trigger for relapse or a substitute addiction.
    Medical professionals caution that kratom’s effects on the brain are similar to opioids, and its use
    may undermine recovery efforts. In fact, some patients have developed kratom use disorder and
    required treatment with medications like buprenorphine/naloxone[6].
    What Do the FDA and DEA Say?
    The FDA has issued multiple warnings about kratom, citing its potential for abuse and serious health
    risks. It has recommended that 7-hydroxymitragynine, a potent compound found in kratom, be
    classified as a Schedule I controlled substance, alongside heroin and fentanyl[7].
    The DEA has listed kratom as a “Drug and Chemical of Concern” but has not yet scheduled it
    federally. However, several states have banned or regulated kratom, and more legislation is under
    consideration[8].
    Office | 3541 Randolph Rd Ste 303 Charlotte, NC 28211
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    For Patients, Families, and Professionals: What Should
    You Do?
    If You’re in Recovery:
  • Talk to your healthcare provider before using kratom.
  • Be cautious of products marketed as “natural” or “safe.”
  • Know that kratom can trigger cravings or withdrawal symptoms.
    If You Think You Might Have OUD:
  • Seek professional help. Kratom is not a substitute for evidence-based treatment.
  • Medications like buprenorphine, methadone, and naltrexone are FDA-approved and clinically
    tested.
    If You’re a Loved One:
  • Stay informed and supportive.
  • Encourage open conversations about substance use and recovery.
  • Help your loved one connect with qualified treatment providers.
    If You’re a Medical or Counseling Professional:
  • Educate patients about the risks and limitations of kratom.
  • Screen for kratom use during assessments.
  • Stay updated on emerging research and regulatory changes.
    Final Thoughts
    Kratom is a complex and controversial substance. While some individuals report benefits, the risks—
    especially for those affected by opioid use disorder—are significant. At our practice, we prioritize
    evidence-based care, patient safety, and long-term recovery. If you have questions about kratom
    or opioid treatment options, we’re here to help.
    Office | 3541 Randolph Rd Ste 303 Charlotte, NC 28211
    Phone|704-246-4644 Fax|704-943-3725 Web|startbupe.com
    Need support or want to learn more?
    Contact our office to speak with a provider or schedule a confidential consultation.

References References
[1] nida.nih.gov
[2] medclinres.org
[3] www.mayoclinic.org
[4] www.fda.gov
[5] www.cvcoalition.org
[6] calhospitalcompare.org

[7] denvergazette.com
[8] www.congress.gov

Reviewed by a medical professional